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Products:Neuroscience >> Cell Adhesion Proteins >> ECM Proteins
Overview
Product name
Anti-TAG1 antibody
See all TAG1 products (4) ...
Description
Rabbit polyclonal to TAG1
Tested applications
WB, IHC-P, IHC-Frmore details
Cross reactivity
Reacts with
Mouse, Rat
Immunogen
A synthetic peptide as a part of rat and mouse TAG1 conjugated to an immunogenic carrier protein
Properties
Form
Lyophilised:
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: Whole serum
Concentration
Concentration information loading...
Purity
Whole antiserum
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Invasion/microenvironment >> ECM >> Cell adhesion >> Other
Neuroscience >> Neurology process >> Growth and Development >> Axonal Guidance Proteins
Neuroscience >> Cell Adhesion Proteins >> ECM Proteins
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - TAG1 antibody (ab68945)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab68945 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/300 - 1/3000.Predicted molecular weight: 114 kDa.
IHC-P: 1/300 - 1/3000.Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
IHC-Fr
IHC-Fr: 1/300 - 1/3000.IHC-Fr: 1/300 - 1/3000.
Target
Function
May play a role in the initial growth and guidance of axons. May be involved in cell adhesion.
Sequence similarities
Belongs to the immunoglobulin superfamily. Contactin family.
Contains 4 fibronectin type-III domains.
Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
Cellular localization
Cell membrane. Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.
Target information above from: UniProt accessionQ02246
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Axonal glycoprotein TAG 1 antibody
- Axonal glycoprotein TAG-1 antibody
- Axonal glycoprotein TAG1 antibody
see all
Database links
- Entrez Gene: 21367 Mouse
- Entrez Gene: 25356 Rat
- SwissProt: 260861 Mouse
- SwissProt: Q61330 Mouse
- SwissProt: 89910 Rat
- SwissProt: P22063 Rat
- Unigene: 260861 Mouse
- Unigene: 89910 Rat
Anti-TAG1 antibody images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - TAG1 antibody (ab68945)
ab68945 at a 1/200 dilution staining TAG1 in rat spinal cord tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Incubated overnight at 4°C, developed with DAB/Ni and counterstained with hematoxylin.
References for Anti-TAG1 antibody (ab68945)
This product has been referenced in:
- Tsai NPet al. Kappa opioid receptor contributes to EGF-stimulated neurite extension in development. Proc Natl Acad Sci U S A 107:3216-21 (2010). WB; Mouse.Read more (PubMed: 20133770) »
- Ashique AMet al. The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis. Sci Signal 2:ra70 (2009).Read more (PubMed: 19887680) »
See all 2 publications for this product
Publishing research using ab68945? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"