Anti-TARBP1 antibody (ab42871)

Overview

• Product nameAnti-TARBP1 antibodySee all TARBP1 primary antibodies ...
• Description
  Rabbit polyclonal to TARBP1

  This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

• Species reactivity
  
  Predicted to work with: Human
• Immunogen

  Synthetic peptide conjugated to KLH derived from within residues 600 - 700 of Human TARBP1.

  Read Abcam's proprietary immunogen policy

  (Peptide available as ab42870.)

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: 1% BSA, PBS, pH 7.4
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Microbiology
  • Organism
  • Virus
  • RNA Virus
  • ssRNA positive strand virus
  • HIV

  • Epigenetics and Nuclear Signaling
  • Chromatin Binding Proteins
  • DNA / RNA binding

  • Immunology
  • Immune System Diseases
  • Antiviral Signaling
  • HIV-related

Applications

Target

• FunctionProbable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA.
• Sequence similaritiesBelongs to the RNA methyltransferase TrmH family.

Target information above from: UniProt accession Q13395 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 6894 Human
  • Omim: 605052 Human
  • SwissProt: Q13395 Human
  • Unigene: 498115 Human

• Alternative names
  FLJ30482 antibodyProbable methyltransferase TARBP1 antibodyTAR (HIV) RNA Binding Protein 1 antibody

  TAR antibodyTAR RNA Binding Protein 1 antibodyTAR RNA loop binding protein antibodyTAR RNA-binding protein 1 antibodyTAR RNA-binding protein of 185 kDa antibodyTARB1_HUMAN antibodyTARBP1 antibodyTRM3 antibodyTRP-185 antibodyTRP185 antibody

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