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Overview

  • Product nameTARBP1 peptide
  • Protein descriptionSynthetic peptide derived from within residues 600 - 700 of Human TARBP1.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab42871 - TARBP1 antibody.
  • Protein length1621 amino acids
  • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas
  • Applications

  • Application notesThis peptide can be used with studies using ab42871.
  • Protein info

    • Alternative names
        FLJ30482Probable methyltransferase TARBP1TAR
        TAR (HIV) RNA Binding Protein 1TAR RNA Binding Protein 1TAR RNA loop binding proteinTAR RNA-binding protein 1TAR RNA-binding protein of 185 kDaTARB1_HUMANTARBP1TRM3TRP-185TRP185
      see all
  • FunctionProbable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA.
  • Sequence similaritiesBelongs to the RNA methyltransferase TrmH family.
  • Target information above from: UniProt accession Q13395 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for TARBP1 peptide (ab42870)

    ab42870 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"