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Western blot - TARDBP protein (Human) (ab75468)
(enlarge)
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Product Name
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TARDBP protein (Human)
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Product type
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Proteins and Peptides
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Peptide
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Recombinant fragment (aa 1-259) human TARDBP protein.
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Tested applications
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ELISA, Inhib, WB
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
Inhib: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Research areas
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Chromatin and Nuclear Signaling >> Transcription >> Other factors
Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Chromatin and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Splicing
Neuroscience >> Neurology process >> Neurodegenerative disease >> Amyotrophic lateral sclerosis
Microbiology >> Organism >> Virus >> RNA Virus >> ssRNA positive strand virus >> HIV
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Relevance
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HIV1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV1 transcription. In addition, this protein regulates alternate splicing of the CFTR (Cystic Fibrosis Transmembrane Regulator) gene.
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Storage buffer
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Preservative: None
Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5 Material safety datasheet (MSDS) for this product:
Glycerol MSDS
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Purification notes
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Purified.
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Form
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Liquid
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Concentration
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0.100 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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Expression system
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E. coli
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this TARDBP protein (Human) is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for TARDBP protein (Human) images, references, products related to ab75468 and other tools.
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TARDBP protein (Human) images:
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 Western blot - TARDBP protein (Human) (ab75468)
SDS-PAGE: Analysis of TARDBP Recombinant Protein
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Search PubMed (MEDLINE) for references to TARDBP
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TARDBP protein (Human) - more information
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Customer reviews (feedback) regarding TARDBP protein (Human) |
Customer FAQs regarding TARDBP protein (Human) |
Protocols for TARDBP protein (Human) |
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TARDBP protein (Human) - related products:
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TARDBP protein (Human) - other tools:
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Contact Abcam with a Technical Enquiry about TARDBP protein (Human) |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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