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- Secondary antibodies
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Product name
Anti-TBLR1 antibody
See all TBLR1 products (6) ...
Description
Rabbit polyclonal to TBLR1
Tested applications
Cross reactivity
Reacts with
Mouse, Rat, Human
Immunogen
Synthetic peptide: WPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVK RLKENADLEWT , corresponding to amino acids 200-250 of Human TBLR1.
WPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVK RLKENADLEWT
Positive control
Tested with human brain cell lysate.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: PBS, 0.2% gelatin.
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Lipid and lipoprotein metabolism >> Lipid metabolism
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Epigenetics and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Co-activators/co-repressors
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- TBLR1 antibody (ab13799)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab13799 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
Application notes
WB: Use at a concentration of 1-3 µg/ml. Detects a band of approximately 61 and 54 kDa (predicted molecular weight: 76 kDa).
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
Tissue specificity
Ubiquitous.
Sequence similarities
Belongs to the WD repeat EBI family.
Contains 1 F-box-like domain.
Contains 1 LisH domain.
Contains 8 WD repeats.
Domain
The F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.
Post-translational
modifications
Phosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localization
Nucleus.
Target information above from: UniProt accessionQ9BZK7
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- C21 antibody
- DC42 antibody
- F box like/WD repeat containing protein TBL1XR1 antibody
see all
Database links
- Entrez Gene: 79718 Human
- Entrez Gene: 81004 Mouse
- Entrez Gene: 365755 Rat
- Omim: 608628 Human
- SwissProt: Q9BZK7 Human
- SwissProt: Q8BHJ5 Mouse
- Unigene: 581171 Human
- Unigene: 202966 Mouse
see all
Anti-TBLR1 antibody images:
- TBLR1 antibody (ab13799)
Western blot analysis of the two forms of TBLR1 in 20
References for Anti-TBLR1 antibody (ab13799)
ab13799 has not yet been referenced specifically in any publications.
Publishing research using ab13799? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"