Overview

  • Product name
  • Description
    Rabbit polyclonal to TBX5
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Zebrafish
  • Immunogen

    Recombinant fragment within Zebrafish TBX5 aa 20-262. The exact sequence is proprietary.
    Database link: Q9IAK8

  • Positive control
    • Zebrafish eye whole cell lysate; Zebrafish tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab210111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Suggested antigen retrieval using 1mM EDTA-NaOH (pH8.0) at 95°C,1Hr

WB 1/500 - 1/3000. Predicted molecular weight: 55 kDa.

Target

  • Function
    Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
  • Involvement in disease
    Defects in TBX5 are the cause of Holt-Oram syndrome (HOS) [MIM:142900]. HOS is a developmental disorder affecting the heart and upper limbs. It is characterized by thumb anomaly and atrial septal defects.
  • Sequence similarities
    Contains 1 T-box DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Holt Oram syndrome antibody
    • HOS antibody
    • T box 5 antibody
    • T box protein 5 antibody
    • T box transcription factor TBX 5 antibody
    • T box transcription factor TBX5 antibody
    • T-box protein 5 antibody
    • T-box transcription factor TBX5 antibody
    • TBX 5 antibody
    • TBX5 antibody
    • TBX5_HUMAN antibody
    • Transcription factor T box 5 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Zebrafish tissue labeling TBX5 with ab210111 at 1/300 dilution.

  • Anti-TBX5 antibody (ab210111) at 1/500 dilution + Zebrafish eye whole cell lysate at 30 µg

    Predicted band size : 55 kDa

    10% SDS PAGE

References

ab210111 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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