Overview

  • Product name
  • Description
    Mouse polyclonal to TC10
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Full length protein corresponding to amino acids 1-205 of Human TC10 (NP_036381.2).

  • Positive control
    • TC10 transfected 293T cell lysate. HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab168645 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa.
ICC/IF Use a concentration of 10 µg/ml.

Target

  • Function
    Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
  • Sequence similarities
    Belongs to the small GTPase superfamily. Rho family.
  • Post-translational
    modifications
    May be post-translationally modified by both palmitoylation and polyisoprenylation.
  • Cellular localization
    Cytoplasm. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARHQ antibody
    • Ras homolog gene family member Q antibody
    • RAS like family 7 member A antibody
    • Ras like protein family member 7A antibody
    • Ras like protein TC10 antibody
    • Ras related GTP binding protein TC10 antibody
    • Ras-like protein family member 7A antibody
    • Ras-like protein TC10 antibody
    • RASL7A antibody
    • Rho related GTP binding protein RhoQ antibody
    • Rho-related GTP-binding protein RhoQ antibody
    • Rhoq antibody
    • RHOQ_HUMAN antibody
    • TC10A antibody
    see all

Anti-TC10 antibody images

  • All lanes : Anti-TC10 antibody (ab168645) at 1 µg/ml

    Lane 1 : TC10 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution
    Developed using the ECL technique

    Predicted band size : 23 kDa
  • Immunofluorescence analysis of HeLa cells, labeling TC10 with ab168645 at 10 µg/ml.

References for Anti-TC10 antibody (ab168645)

This product has been referenced in:
  • Mayer S  et al. Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission. Proc Natl Acad Sci U S A 110:20795-800 (2013). Read more (PubMed: 24297911) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab168645.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up