Overview

  • Product name
    Anti-TCEAL7 antibody
  • Description
    Rabbit polyclonal to TCEAL7
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Cow, Cat, Dog, Human, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 40-89 (RLLQSLEEFK EDIDYRHFKG EEMTGEEEEM ERCLEEIRSL RKKFRALHSN) of Mouse TCEAL7 (NP_001120641).

  • Positive control
    • Mouse small intestine lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab122945 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 12 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.
  • Tissue specificity
    Highly expressed in normal and fetal brain tissues, and weakly expressed in uterus and ovary. Down-regulated in epithelial ovarian, cervical, prostate, breast, brain and lung cancer cell lines and in brain and ovarian tumors.
  • Sequence similarities
    Belongs to the TFS-II family. TFA subfamily.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1110018P05Rik antibody
    • AI118095 antibody
    • LL0XNC01-105G4.1 antibody
    • MPMGp800C04260Q003 antibody
    • RP23-105O4.2 antibody
    • TCAL7_HUMAN antibody
    • TCEA-like protein 7 antibody
    • TCEAL7 antibody
    • Transcription elongation factor A protein-like 7 antibody
    • Transcription elongation factor S-II protein-like 7 antibody
    see all

Images

  • Anti-TCEAL7 antibody (ab122945) at 1 µg/ml + Mouse small intestine lysate at 10 µg

    Predicted band size : 12 kDa

References

ab122945 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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