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Products:Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin
Overview
Product name
Anti-TCP1 alpha antibody
See all TCP1 alpha products (11) ...
Description
Mouse monoclonal to TCP1 alpha
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-557 of Human TCP1 alpha
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
kappa
Research areas
Signal Transduction >> Protein Trafficking >> Chaperones >> Other Chaperones
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin
Applications
Show applications key
Our Abpromise guarantee covers the use of ab57684 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.
Sequence similarities
Belongs to the TCP-1 chaperonin family.
Cellular localization
Cytoplasm. Cytoplasm > cytoskeleton > centrosome.
Target information above from: UniProt accessionP17987
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- AI528772 antibody
- c-cpn antibody
- CCT alpha antibody
see all
Database links
- Entrez Gene: 6950 Human
- Omim: 186980 Human
- SwissProt: P17987 Human
- Unigene: 363137 Human
Anti-TCP1 alpha antibody images:
IHC-P - TCP1 alpha antibody (ab57684)
TCP1 alpha antibody (ab57684) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.
Western blot - TCP1 alpha antibody (ab57684)
TCP1 alpha antibody (ab57684) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-TCP1 alpha antibody (ab57684)
ab57684 has not yet been referenced specifically in any publications.
Publishing research using ab57684? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"