Assuming 100µl/well, a concentration of 1.0-2.0 µg/ml of ab625 will detect at least 300 pg/ml of recombinant human TECK when used with ab83146 as the detection antibody at a concentration of approximately 0.5-1.0 µg/ml.
FunctionPotentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1.
Tissue specificitySpecifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.