Anti-TFB2M antibody (ab107685)

Overview

• Product nameAnti-TFB2M antibodySee all TFB2M primary antibodies ...
• Description
  Rabbit polyclonal to TFB2M
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide conjugated to KLH, corresponding to C terminal amino acids 375-404 of Human TFB2M (NP_071761.1).

• Positive controlWiDr cell line lysates

Properties

• FormLiquid
• Storage instructionsStore at 4°C (up to 6 months). For long term storage store at -20°C
• Storage bufferPreservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesThis antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Nucleotide metabolism
  • Molecular processes
  • Mitochondrial transcription

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial markers

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial Biogenesis

  • Other Factors

  • Tags & Cell Markers
  • Subcellular Markers
  • Organelles
  • Mitochondria

Applications

Target

• FunctionS-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
• Tissue specificityUbiquitously expressed.
• Sequence similaritiesBelongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.
• Cellular localizationMitochondrion.

Target information above from: UniProt accession Q9H5Q4 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 64216 Human
  • Omim: 607055 Human
  • SwissProt: Q9H5Q4 Human
  • Unigene: 7395 Human
  • Unigene: 726304 Human

• Alternative names
  N''-adenosyl(rRNA) dimethyltransferase 2 antibody S adenosylmethionine 6 N', N' adenosyl(rRNA) dimethyltransferase 2 antibodyDimethyladenosine transferase 2 antibody

  FLJ22661 antibodyFLJ23182 antibodyh-mtTFB antibodyh-mtTFB2 antibodyHCV NS5A transactivated protein 5 antibodyHCV NS5A-transactivated protein 5 antibodyHepatitis C virus NS5A-transactivated protein 5 antibodyHkp1 antibodyhTFB2M antibodyMitochondrial 12S rRNA dimethylase 2 antibodymitochondrial antibodyMitochondrial dimethyladenosine transferase 2 antibodyMitochondrial transcription factor B2 antibodymtTFB antibodymtTFB2 antibodyNS5ATP5 antibodyS-adenosylmethionine-6-N'' antibodyTFB2M antibodyTFB2M_HUMAN antibodyTranscription Factor B2 antibodyTranscription factor B2 mitochondrial antibody

  see all

Anti-TFB2M antibody images

• 

  Western blot - TFB2M antibody (ab107685)
  Anti-TFB2M antibody (ab107685) at 1/100 dilution + WiDr cell line lysates at 35 µg
  
  Predicted band size : 45 kDa