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Products:Immunology >> Adaptive Immunity >> T Cells >> Non-CD
Overview
Product name
Anti-TIM 1 antibody
See all TIM 1 products (9) ...
Description
Rabbit polyclonal to TIM 1
Tested applications
Cross reactivity
Reacts with
Mouse, Human
Predicted to work with
Chimpanzee, Monkey, African Green Monkey
Immunogen
A portion of amino acids 200-300 of human TIM 1 protein.
Positive control
Human or mouse brain tissue lysate.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: 0.05% BSA, PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Immunology >> Immune System Diseases >> Allergens
Microbiology >> Interspecies Interaction >> Host Virus Interaction
Immunology >> Adaptive Immunity >> T Cells >> Non-CD
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Western blot - TIM 1 antibody (ab47068)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab47068 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 3 µg/ml.Detects a band of approximately 21 kDa (predicted molecular weight: 39 kDa).
Target
Function
May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair.
Tissue specificity
Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses.
Sequence similarities
Belongs to the immunoglobulin superfamily. TIM family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Cellular localization
Membrane.
Target information above from: UniProt accessionQ96D42
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- HAVCR 1 antibody
- HAVcr-1 antibody
- Havcr1 antibody
see all
Database links
- Entrez Gene: 26762 Human
- Entrez Gene: 171283 Mouse
- Omim: 606518 Human
- SwissProt: Q96D42 Human
- SwissProt: Q5QNS5 Mouse
- Unigene: 129711 Human
Anti-TIM 1 antibody images:
Western blot - TIM 1 antibody (ab47068)
All lanes : Anti-TIM 1 antibody (ab47068) at 1 µg/ml
Lane 1 : Human brain lysate with no immunizing peptide
Lane 2 : Human brain lysate with immunizing peptide
Lane 3 : Mouse brain lysate
Predicted band size : 39 kDa
Observed band size : 21 kDa (why is the actual band size different from the predicted?)
References for Anti-TIM 1 antibody (ab47068)
ab47068 has not yet been referenced specifically in any publications.
Publishing research using ab47068? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"