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Overview

  • Product nameTL1A proteinSee all TL1A proteins and peptides ...
  • Protein descriptionRecombinant fragment, corresponding to amino acids 68-239 of Chicken TL1A expressed in yeast; 172 amino acids, Predicted MWt 19.1 kDa (UniProt Q50L61).
  • Expression hostYeast

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesPurified by Ion-exchange chromatography
  • FormLyophilised:Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
  • Storage instructionsStore at -20°C. Stable for 12 months at -20°C
  • Storage bufferPreservative: None
    Constituents: 10% Trehalose, 1X PBS
  • Concentration information loading...
  • Additional notesReconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
  • Sequence notesERSSHFLKQR AVAAVTDTLP SAEKPRAHLT VKKQEPSSTT GSHLPILQWE DKRGLAFTKN NLSYSSNALV IPVSGDYYVY AQVTFRGPSD TSSKTSSVTA VITKVTDSYP EPTQLLTSTK TLSEERNNWF QPIYLGAVVS LEIGDKLMVN VSDIKLVDYT KEHKTFFGAF LL
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab90800 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        MGC129934MGC129935tl1
        TL1 Atl1atnf ligand related molecule 1TNF ligand-related molecule 1tnf superfamily ligand tl1aTNF15_HUMANtnfsf15Tumor necrosis factor (ligand) superfamily member 15Tumor necrosis factor ligand superfamily member 15Tumor necrosis factor ligand superfamily member 15, secreted formVascular endothelial cell growth inhibitorVascular endothelial growth inhibitorVascular endothelial growth inhibitor 192avegiVEGI192A
      see all
  • FunctionReceptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
  • Tissue specificitySpecifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
  • Sequence similaritiesBelongs to the tumor necrosis factor family.
  • Cellular localizationSecreted and Membrane.

    • Target information above from: UniProt accession O95150 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for TL1A protein (ab90800)

    ab90800 has not yet been referenced specifically in any publications.

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