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Anti-TLR10 antibody (ab21273)

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Overview

Product name

Anti-TLR10 antibody
See all TLR10 products (5) ...

Description

Rabbit polyclonal to TLR10

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Synthetic peptide corresponding to 14 amino acids near the middle of TLR10 (Human).

Positive control

Human lymph node cell lysate.

Properties

Form

Liquid

Storage instructions

Store at +4°C.

Storage buffer

Preservative: 0.02% Sodium Azide
Constituents: PBS

Concentration

Concentration information loading...

Purification notes

Ion exchange chromatography.

Clonality

Polyclonal

Isotype

IgG

Research areas

Immunology >> Innate Immunity >> TLR Signaling
Immunology >> Immunoglobulins >> Receptors
Immunology >> Innate Immunity >> Macrophage / Inflamm.

  • Western blot - TLR10 antibody (ab21273)Western blot - TLR10 antibody (ab21273) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab21273 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Tissue specificity

Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.

Sequence similarities

Belongs to the Toll-like receptor family.
Contains 15 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain.

Cellular localization

Membrane.

Target information above from: UniProt accessionQ9BXR5 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • CD 290 antibody
  • CD 290 antigen antibody
  • CD290 antibody
  • CD290 antigen antibody
  • MGC104967 antibody
  • MGC126398 antibody
  • MGC126399 antibody
  • OTTHUMP00000158729 antibody
  • OTTHUMP00000218162 antibody
  • TLR10 antibody
  • TLR10_HUMAN antibody
  • Toll like receptor 10 antibody
  • Toll-like receptor 10 antibody
  • UNQ315/PRO358 antibody
see all

Database links

Anti-TLR10 antibody images:

  Western blot - TLR10 antibody (ab21273)

Western blot - TLR10 antibody (ab21273)

Lane 1 : Anti-TLR10 antibody (ab21273) at 0.5 µg/ml
Lane 2 : Anti-TLR10 antibody (ab21273) at 1 µg/ml

Lane 1 : Human lymph node cell lysates
Lane 2 : Human lymph node cell lysates


Predicted band size : 94 kDa
Observed band size : 75 kDa (why is the actual band size different from the predicted?)

References for Anti-TLR10 antibody (ab21273)

ab21273 has not yet been referenced specifically in any publications.

Publishing research using ab21273? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"