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Product Name
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TLR9 antibody [5G5]
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See all TLR9 antibodies (15)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [5G5] to TLR9
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Reacts with
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Ms
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Does not react with
(species key)
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Hu
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Specificity
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This antibody reacts very well in mouse, but more weakly in human. There are references available which suggest the antibody works well in human, however, customer feedback suggests results in human can be inconsistant.
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Tested applications
(see key)
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Flow Cyt, IHC-Fr, IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Flow Cyt: 1/50.
IHC-Fr: 1/50.Ab16892 stains RAW macrophages and TLR9 transfected HEK293 cells.
IHC-P: Use at an assay dependent dilution.
WB: 1/50. Predicted molecular weight: 116 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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RAW macrophages
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Cellular localization
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Cell Membrane, Type I membrane protein.
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Research areas
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Immunology >> Innate Immunity >> TLR Signaling
Signal Transduction >> Adapters >> Transmembrane
Immunology >> Immunoglobulins >> Receptors
Immunology >> Innate Immunity >> Macrophage / Inflamm.
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Relevance
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TLR9 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The gene encoding this protein is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
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TLR9 antibody [5G5] (ab16892) |
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Database links
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The links below go to external sites and will open in a new browser window Entrez Gene | | 81897 (Mouse)
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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5G5
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Isotype
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IgG2a
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 0.1% BSA, PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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Provided as a 0.2µm filtered antibody solution
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Form
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Liquid
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Concentration
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0.100 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this TLR9 antibody [5G5] is on this datasheet. But please do contact us if you would like any reassurance! |
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References for TLR9 antibody [5G5] (ab16892)
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This product has been used in:
Ilversaro et al Toll like receptor 9 agonists stimulate prostate cancer invasion in vitro The Prostate 67:774-781 (2007).
If you publish research using ab16892 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to TLR9
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TLR9 antibody [5G5] - more information
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Customer reviews (feedback) regarding TLR9 antibody [5G5] |
Customer FAQs regarding TLR9 antibody [5G5] |
Protocols for TLR9 antibody [5G5] |
Price and availability of products related to TLR9 antibody [5G5] |
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TLR9 antibody [5G5] - related products:
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TLR9 antibody [5G5] - other tools:
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Contact Abcam with a Technical Enquiry about TLR9 antibody [5G5] |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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