You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Anti-TMEPAI antibody (ab57503)

CodeSizePriceAbpointsAvailability
    
Add to basket
 

  • -

  •   
  •   
  •   

  •  

  •  
  •  

  •  

  •  
Updating...

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »

Overview

Product name

Anti-TMEPAI antibody
See all TMEPAI products (3) ...

Description

Mouse monoclonal to TMEPAI

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant fragment: NRTIFDSDLM DSARLGGPCP PSSNSGISAT CYGSGGRMEG PPPTYSEVIG HYPGSSFQHQ QSSGPPSLLE GTRLHHTHIA PLESAAIWSK EKDKQKGHPL , corresponding to amino acids 181-281 of Human TMEPAI

NRTIFDSDLMDSARLGGPCPPSSNSGISATCYGSGGRMEG PPPTYSEVIGHYPGSSFQHQQSSGPPSLLEGTRLHHTHIA PLESAAIWSKEKDKQKGHPL

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Isotype

IgG2a

Light chain type

kappa

Research areas

Signal Transduction >> Growth Factors/Hormones >> Hormones

  • Western blot - TMEPAI antibody (ab57503)Western blot - TMEPAI antibody (ab57503) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab57503 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

WB: Use at a concentration of 1-5 µg/ml.

This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Involved in down-regulation of the androgen receptor (AR). Enhances ubiquitination and proteasome-mediated degradation of AR, probably by recruiting NEDD4.

Tissue specificity

Highest expression in prostate. Also expressed in ovary.

Sequence similarities

Belongs to the PMEPA1 family.

Domain

The WW-binding motifs mediate interaction with NEDD4.

Cellular localization

Cell membrane.

Target information above from: UniProt accessionQ969W9 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • PMEPA1 antibody
  • PMEPA_HUMAN antibody
  • Prostate transmembrane protein, androgen induced 1 antibody
  • Solid tumor associated 1 protein antibody
  • Solid tumor-associated 1 protein antibody
  • STAG1 antibody
  • TMEPAI antibody
  • Transmembrane prostate androgen induced protein antibody
  • Transmembrane prostate androgen-induced protein antibody
  • Transmembrane, prostate androgen induced RNA antibody
see all

Database links

Anti-TMEPAI antibody images:

  Western blot - TMEPAI antibody (ab57503)

Western blot - TMEPAI antibody (ab57503)

Western blot against tagged recombinant protein immunogen using ab57503 TMEPAI antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

References for Anti-TMEPAI antibody (ab57503)

This product has been referenced in:

  • Saadi A  et al. Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers. Proc Natl Acad Sci U S A 107:2177-82 (2010). IHC-P; Human.Read more (PubMed: 20080664) »

See 1 publication for this product

Publishing research using ab57503? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"