Recombinant Anti-HESP antibody [EPR12943(2)-44] (ab187669)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR12943(2)-44] to HESP
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
Overview
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Product name
Anti-HESP antibody [EPR12943(2)-44]
See all HESP primary antibodies -
Description
Rabbit monoclonal [EPR12943(2)-44] to HESP -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Human fetal liver, HepG2, T47D, WI38, mouse spleen and PC12 cell lysates.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR12943(2)-44 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab187669 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/10000. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa).
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Notes |
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WB
1/1000 - 1/10000. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa). |
Target
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Function
Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest. -
Tissue specificity
Expressed in esophagus, liver, colon and lung. Down-regulated in esophagus cancers. -
Sequence similarities
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
Contains 1 SEA domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 339967 Human
- Entrez Gene: 194597 Mouse
- Entrez Gene: 686581 Rat
- Omim: 611704 Human
- SwissProt: Q6ZMR5 Human
- SwissProt: Q3UQ41 Mouse
- Unigene: 450110 Human
- Unigene: 249106 Mouse
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Alternative names
- Airway trypsin-like protease 1 antibody
- ECRG1 antibody
- epidermal type II transmembrane serine protease antibody
see all
Images
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All lanes : Anti-HESP antibody [EPR12943(2)-44] (ab187669) at 1/5000 dilution
Lane 1 : Human fetal liver lysate
Lane 2 : HepG2 cell lysate
Lane 3 : T47D cell lysate
Lane 4 : WI38 cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 48 kDa -
All lanes : Anti-HESP antibody [EPR12943(2)-44] (ab187669) at 1/1000 dilution
Lane 1 : mouse spleen cell lysate
Lane 2 : PC12 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 48 kDa
Datasheets and documents
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SDS download
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Datasheet download
Certificate of Compliance
References (0)
ab187669 has not yet been referenced specifically in any publications.