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Anti-TNF Receptor II antibody, prediluted (ab15564)

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Overview

  • Product nameAnti-TNF Receptor II antibody, predilutedSee all TNF Receptor II primary antibodies ...
  • Description
    Rabbit polyclonal to TNF Receptor II, prediluted
  • Tested applicationsIHC-P more details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Mouse) (C terminal).

  • Positive controlThymus

Properties

Applications

Our Abpromise guarantee covers the use of ab15564 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IHC-P
  • Application notesIHC-P: Working dilution: Ready-to-use for 30 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionReceptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
    • Sequence similaritiesContains 4 TNFR-Cys repeats.
    • Post-translational
      modifications      Phosphorylated; mainly on serine residues and with a very low level on threonine residues.
      A soluble form (tumor necrosis factor binding protein 2) is produced from the membrane form by proteolytic processing.
    • Cellular localizationSecreted and Cell membrane.

      • Target information above from: UniProt accession P20333 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      see all
    • Alternative names
        CD 120b antibodyCD120b antibodyCD120b antigen antibody
        Etanercept antibodyp75 antibodyp75TNFR antibodyp80 TNF alpha receptor antibodyp80 TNF-alpha receptor antibodyTBP-2 antibodyTBP2 antibodyTBPII antibodyTNF R II antibodyTNF R2 antibodyTNF R75 antibodyTNF-R2 antibodyTNF-RII antibodyTNFBR antibodyTNFR 2 antibodyTNFR-II antibodyTNFR2 antibodyTNFR75 antibodyTNFR80 antibodyTNFRII antibodyTNFRSF 1B antibodyTNFRSF1B antibodyTNR1B antibodyTNR1B_HUMAN antibodyTumor necrosis factor beta receptor antibodyTumor necrosis factor binding protein 2 antibodyTumor necrosis factor receptor 2 antibodyTumor necrosis factor receptor superfamily member 1B precursor antibodyTumor necrosis factor receptor type II antibodyTumor necrosis factor-binding protein 2 antibody
      see all

    Anti-TNF Receptor II antibody, prediluted images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - TNF Receptor II antibody, prediluted (ab15564)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - TNF Receptor II antibody, prediluted (ab15564)
      ab15564 staining TNF Receptor II in thymus by Immunohistochemistry (FFPE-sections).

    References for Anti-TNF Receptor II antibody, prediluted (ab15564)

    ab15564 has not yet been referenced specifically in any publications.

    Publishing research using ab15564 ? Please let us know so that we can cite the reference in this datasheet

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