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Western blot - TNFAIP3 antibody (ab14223)
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Product Name
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TNFAIP3 antibody
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See all TNFAIP3 antibodies (5)...
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Product type
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Primary antibodies
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Description
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Chicken polyclonal to TNFAIP3
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Immunogen
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Synthetic peptide: LRSSQRRDVP RTTQSTSRPK CARASCKNILA CRSEELCMEC QHPNQRMGPGA HRGEPAPEDP PKQRCRAPAC DHFGNAKCNGY CNECFQFKQMYG, corresponding to amino acids 696-790 of Human TNFAIP3.
BLAST 'LRSSQRRDVP RTTQSTSRP K CARASCKN ILA CRSEEL CMEC QHPNQ RMGPGA HRG EPAPEDP PK QRCRAPAC D HFGNAKCNGY CNECFQFKQ ' with  or 
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Reacts with
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Hu, Ms
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Tested applications
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IHC-Fr, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-Fr: Use at an assay dependent dilution (PMID 18006655).
WB: Use at an assay dependent dilution. Detects a band of approximately 70 kDa (predicted molecular weight: 90 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic and Nuclear
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Research areas
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Cancer >> Growth factors >> TNF
Signal Transduction >> Growth Factors/Hormones >> TNF
Immunology >> Innate Immunity >> Cytokines >> TNF Superfamily
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Relevance
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TNFAIP3 interacts with NAF1 and inhibits TNF induced NF kappa B dependent gene expression by interfering with a RIP or TRAF2 mediated transactivation signal. It inhibits programmed cell death, has a role in the function of the lymphoid system, and may contribute to the in vivo effects of TNF.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Chicken
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Clonality
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Polyclonal
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Isotype
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IgY
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: None
Constituents: PBS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this TNFAIP3 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for TNFAIP3 antibody images, references, products related to ab14223 and other tools.
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TNFAIP3 antibody images:
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 Western blot - TNFAIP3 antibody (ab14223)
Predicted band size : 90 kDa
E coli derived fusion protein as antigen. ab14223 dilution 1/2000 goat anti HRP dilution 1/1000.
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References for TNFAIP3 antibody (ab14223)
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This product has been used in:
Wolfrum S et al. The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-kappaB target genes. Proc Natl Acad Sci U S A 104:18601-6 (2007). IHC-Fr; Mouse. PubMed: 18006655
If you publish research using ab14223 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to TNFAIP3
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TNFAIP3 antibody - more information
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Customer reviews (feedback) regarding TNFAIP3 antibody |
Customer FAQs regarding TNFAIP3 antibody |
Protocols for TNFAIP3 antibody |
Price and availability of products related to TNFAIP3 antibody |
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TNFAIP3 antibody - related products:
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TNFAIP3 antibody - other tools:
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Contact Abcam with a Technical Enquiry about TNFAIP3 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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