![Flow Cytometry / FACS - TRAIL antibody [B-S23] (Biotin) (ab27322) image](#ab27322.gif)
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Product name
Anti-TRAIL antibody [B-S23] (Biotin)
See all TRAIL products (23) ...
Description
Mouse monoclonal [B-S23] to TRAIL (Biotin)
Conjugation
Biotin
Specificity
This antibody recognises the TRAIL antigen.
Tested applications
Flow Cytmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein (Human)
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: 5% BSA, PBS
Concentration
Concentration information loading...
Purity
Ion Exchange Chromatography
Clonality
Monoclonal
Clone number
B-S23
Myeloma
x63-Ag8.653
Isotype
IgG1
Research areas
Cardiovascular >> Atherosclerosis >> Apoptosis
Cancer >> Invasion/microenvironment >> Apoptosis >> Death receptors & ligands >> TRAIL
Cell Biology >> Apoptosis >> Extracellular Signals >> Death Ligands
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Flow Cytometry / FACS - TRAIL antibody [B-S23] (Biotin) (ab27322)
![Flow Cytometry / FACS - TRAIL antibody [B-S23] (Biotin) (ab27322) image](/ps/datasheet/Images/27/ab27322/ab27322.gif)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab27322 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
Flow Cyt
Application notes
Flow Cyt: Use 10 µl to label 106 cells or 100 µl of whole blood.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Tissue specificity
Widespread; most predominant in spleen, lung and prostate.
Sequence similarities
Belongs to the tumor necrosis factor family.
Cellular localization
Membrane.
Target information above from: UniProt accessionP50591
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Apo 2 ligand antibody
- Apo 2L antibody
- Apo-2 ligand antibody
see all
Database links
- Entrez Gene: 8743 Human
- Omim: 603598 Human
- SwissProt: P50591 Human
- Unigene: 478275 Human
Anti-TRAIL antibody [B-S23] (Biotin) images:
Flow Cytometry / FACS - TRAIL antibody [B-S23] (Biotin) (ab27322)
Ab27322, at a dilution of 10µl for 106 cells or 100 µl of whole blood, staining TRAIL by Flow Cytometry.
References for Anti-TRAIL antibody [B-S23] (Biotin) (ab27322)
This product has been referenced in:
- Herbeuval JP et al. TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells. Blood 105:2458-64 (2005).Read more (PubMed: 15585654) »
See 1 publication for this product
Publishing research using ab27322? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"