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Product Name
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TRAP220/MED1 antibody
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See all TRAP220/MED1 antibodies (7)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to TRAP220/MED1
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Immunogen
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Synthetic peptide: HKKEKKKVKD KDRDRDRDKD RDKKKSHSIK PESWSKSPIS SDQSLSMTSN TILSADRPSR LSPDFMIGEE DDDLMDVALI GN, corresponding to C terminal amino acids 1500-1581 of Human TRAP220/MED1
BLAST 'HKKEKKKVKD KDRDRDRDKD RDKKKSHSIK PESWSKSPIS SDQSLSMTSN TILSADRPSR LSPDFMIGEE DDDLMDVALI ' with  or 
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Reacts with
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Hu, Ms
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Predicted to react
(species key)
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Orngt
(Due to sequence homology)
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Tested applications
(see key)
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IP, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IP: Use at an assay dependent dilution.
WB: 1/500 - 1/2500. Predicted molecular weight: 180 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Co-activators/co-repressors
Chromatin and Nuclear Signaling >> Transcription >> Polymerase associated factors >> Pol II Transcription >> Other
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Relevance
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TRAP220/MED1 work with coactivators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53 dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize (referenced from Entrez Gene).
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein A purified
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Storage buffer
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Preservative: 0.02% Thimerosal (merthiolate)
Constituents: 30% Glycerol, 1% BSA, PBS Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Thimerosal MSDS
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Form
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Liquid
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this TRAP220/MED1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to TRAP220/MED1
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TRAP220/MED1 antibody - more information
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Customer reviews (feedback) regarding TRAP220/MED1 antibody |
Customer FAQs regarding TRAP220/MED1 antibody |
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