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Overview

  • Product nameAnti-TRPC5 antibodySee all TRPC5 primary antibodies ...
  • Description
    Rabbit polyclonal to TRPC5
  • Tested applicationsWB, IHC-Fr, IHC-P more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human) conjugated to immunogenic carrier protein

Properties

Applications

Our Abpromise guarantee covers the use of ab70291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
IHC-Fr
IHC-P
  • Application notesIHC-Fr: Use at a concentration of 1 - 10 µg/ml.
    IHC-P: Use at a concentration of 1 - 10 µg/ml. Antigen retrieval is recommended.
    WB: Use at a concentration of 1 - 10 µg/ml. Predicted molecular weight: 111 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionThought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion.
    • Tissue specificityExpressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole.
    • Sequence similaritiesBelongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC5 sub-subfamily.
      Contains 4 ANK repeats.
    • Cellular localizationMembrane.

      • Target information above from: UniProt accession Q9UL62 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          Htrp 5 antibodyHtrp-5 antibodyHtrp5 antibody
          Short transient receptor potential channel 5 antibodyTransient receptor potential cation channel subfamily C member 5 antibodyTransient receptor potential channel 5 antibodyTransient receptor protein 5 antibodyTRP 5 antibodyTRP-5 antibodyTRP5 antibodyTRPC 5 antibodyTrpC5 antibodyTRPC5_HUMAN antibody
        see all

      References for Anti-TRPC5 antibody (ab70291)

      ab70291 has not yet been referenced specifically in any publications.

      Publishing research using ab70291 ? Please let us know so that we can cite the reference in this datasheet

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