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Product Name 

TRRAP antibody

 

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Product type 

Primary antibodies

Description 

Rabbit polyclonal to TRRAP

Immunogen 

Recombinant fragment, corresponding to amino acids 2824-2950 of Human TRRAP.

Reacts with 
(species key)

Hu

Specificity 

Ab10902 recognises the protein TRRAP which also binds to E2F and has sequence similarities to the ATM superfamily.

Tested applications 
(see key)

WB


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
WB: 1/1000. Detects a band of approximately 434 kDa (predicted molecular weight: 438 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> Transcription >> Co-factors
Chromatin and Nuclear Signaling >> Transcription >> Other factors

Relevance 

TRRAP (TRansformation/tRanscription domain Associated Protein) is an adapter protein that is found in a number of multiprotein chromatin complexes with histone acetyltransferase (HAT) activity. These complexes include PCAF, TFTC-HAT, TIP60 HAT, STAGA, and BAF53 complexes. TRRAP is thought to be responsible for the concerted and context-dependent recruitment of these complexes to chromatin during transcription, replication and DNA repair. TRRAP plays a key role in transcriptional activation by c-Myc, p53/TP53, E2F1 and E2F4.

 

Alternative names TRRAP antibody (ab10902)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

8295    (Human)

GeneCard

    

GC07P098087    (Human)

Omim

    

603015    (Human)

SwissProt

    

Q9Y4A5    (Human)

Unigene

    

203952    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Whole antiserum

Storage buffer 

Preservative: 0.09% Sodium Azide

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this TRRAP antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to TRRAP

 

TRRAP antibody - more information

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TRRAP antibody - related products:

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Lysates

 

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