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Product Name
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TRRAP antibody
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See all TRRAP antibodies (5)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to TRRAP
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Immunogen
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Recombinant C-terminal kinase-related domain of TRRAP (Human).
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Reacts with
(species key)
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Hu, Ms
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Specificity
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Ab10904 recognises the protein TRRAP which also binds to E2F and has sequence similarities to the ATM superfamily.
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: 1/2000. Detects a band of approximately 434 kDa (predicted molecular weight: 438 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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HeLa cell lysates.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> Transcription >> Co-factors
Chromatin and Nuclear Signaling >> Transcription >> Other factors
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Relevance
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TRRAP (TRansformation/tRanscription domain Associated Protein) is an adapter protein that is found in a number of multiprotein chromatin complexes with histone acetyltransferase (HAT) activity. These complexes include PCAF, TFTC-HAT, TIP60 HAT, STAGA, and BAF53 complexes. TRRAP is thought to be responsible for the concerted and context-dependent recruitment of these complexes to chromatin during transcription, replication and DNA repair. TRRAP plays a key role in transcriptional activation by c-Myc, p53/TP53, E2F1 and E2F4.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: 0.09% Sodium Azide
Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this TRRAP antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to TRRAP
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TRRAP antibody - more information
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Customer reviews (feedback) regarding TRRAP antibody |
Customer FAQs regarding TRRAP antibody |
Protocols for TRRAP antibody |
Price and availability of products related to TRRAP antibody |
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TRRAP antibody - related products:
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TRRAP antibody - other tools:
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Contact Abcam with a Technical Enquiry about TRRAP antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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