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Anti-TSH alpha antibody [ME.132 ] (ab9510)

Overview

  • Product nameAnti-TSH alpha antibody [ME.132 ]See all TSH alpha primary antibodies ...
  • Description
    Mouse monoclonal [ME.132 ] to TSH alpha
  • SpecificityThis antibody shows cross reactivity with: hCG-beta = <1% hCG-alpha = <1% hLH = <1% hFSH = <1% hTSH = <100% Affinity = 4 x 1010
  • Tested applicationsELISA more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    hTSH-alpha, MW 13.5 kDa

  • General notesP.I. 6.0-7.0

Properties

Applications

Our Abpromise guarantee covers the use of ab9510 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
ELISA ELISA: Use at an assay dependent concentration.

Target

  • RelevanceThyroid stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
      aGSU antibodyalpha GSU antibodyAlphaSU antibody
      Chorionic gonadotropin alpha polypeptide antibodyGlycoprotein hormones alpha chain precursor antibodyGlycoprotein hormones alpha polypeptide antibodyGlycoprotein hormones alpha polypeptide antibodyGPHalpha antibodyThyroid Stimulating Hormone antibodyThyroid Stimulating Hormone antibodyThyroid Stimulation Hormone antibodyThyroid Stimulation Hormone antibodyThyrotropin alpha subunit antibody
    see all

References for Anti-TSH alpha antibody [ME.132 ] (ab9510)

ab9510 has not yet been referenced specifically in any publications.

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We do not have set expiration dates for our products. Most antibodies are stable and can last for anywhere from a few months to several years if stored properly, so we strongly recommend that you follow the storage...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"