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Anti-TWSG1 antibody (ab57552)

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Overview

Product name

Anti-TWSG1 antibody
See all TWSG1 products (2) ...

Description

Mouse monoclonal to TWSG1

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant fragment: AEELSHHENL VSFLETVNQP HHQNVSVPSN NVHAPYSSDK EHMCTVVYFD DCMSIHQCKI SCESMGASKY RWFHNACCEC IGPECIDYGS KTVKCMNCMF , corresponding to amino acids 124-224 of Human TWSG1

AEELSHHENL VSFLETVNQP HHQNVSVPSN NVHAPYSSDK EHMCTVVYFD DCMSIHQCKI SCESMGASKY RWFHNACCEC IGPECIDYGS KTVKCMNCMF

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Isotype

IgG3

Light chain type

kappa

Research areas

Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Neurology process >> Neural Signal Transduction

  • Western blot - TWSG1 antibody (ab57552)Western blot - TWSG1 antibody (ab57552) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab57552 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

WB: Use at a concentration of 1-5 µg/ml.

This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Twisted Gastrulation Protein 1(TWSG1) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins thereby preventing BMPs from binding to their receptors. It can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex.

Cellular localization

Secreted

Alternative names

  • PSEC0250 antibody
  • TSG antibody
  • TSG1 antibody
  • twisted gastrulation homolog 1 antibody
  • Twisted gastrulation protein antibody
see all

Database links

Anti-TWSG1 antibody images:

  Western blot - TWSG1 antibody (ab57552)

Western blot - TWSG1 antibody (ab57552)

Western blot against tagged recombinant protein immunogen using ab57552 TWSG1 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

References for Anti-TWSG1 antibody (ab57552)

ab57552 has not yet been referenced specifically in any publications.

Publishing research using ab57552? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"