You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Overview

  • Product nameTapasin protein (Human)
  • Protein descriptionRecombinant fragment Human Tapasin (197-300 amino acids) with N-terminal proprietary tag. Predicted MW 37.07kDa (UniProt: O15533).
  • Uniprot accessionO15533
  • Molecular weight37.070kDa inclusive of tags
  • Protein length104 amino acids
  • Expression hostWheat germ

    • Properties

  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferpH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl
  • Concentration information loading...
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml
    Best use within three months from the date of receipt of this protein.
  • Sequence notesPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAV AFAAWDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLP YLQGQVTLELAVYKPPKVSLMPAT
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab114877 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    ELISA ELISA: Use at an assay dependent concentration.
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
    WB WB: Use at an assay dependent concentration. Recombinant protein

    Protein info

    • Alternative names
        NGS 17NGS-17NGS17
        TAP associated proteinTAP binding proteinTAP BPTAP-associated proteinTAP-binding proteinTAPATapasinTAPBPTPNTPSNTPSN_HUMAN
      see all
  • FunctionInvolved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
  • Tissue specificityNeutrophils, mostly in fully differentiated cells.
  • Sequence similaritiesContains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • DomainThe N-terminus is required for efficient association with MHC class I molecule and for a stable interaction between MHC I and calreticulin. Binding to TAP is mediated by the C-terminus region.
  • Cellular localizationEndoplasmic reticulum membrane.

    • Target information above from: UniProt accession O15533 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    Tapasin protein (Human) images

    • SDS-PAGE - Tapasin protein (ab114877)
      SDS-PAGE - Tapasin protein (ab114877)
      12.5% SDS-PAGE showing ab114877 at approximately 37.07kDa.
      Stained with Coomassie Blue.

    References for Tapasin protein (Human) (ab114877)

    ab114877 has not yet been referenced specifically in any publications.

    Publishing research using ab114877 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab114877 Submit a Question for ab114877

    There are currently no Abreviews or Questions for ab114877.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"