Overview

  • Product name
  • Description
    Rabbit polyclonal to Tbx4
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide derived from residues 257 - 306 of human Tbx4.

  • Positive control
    • HepG2 cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab28634 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 60 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
  • Involvement in disease
    Defects in TBX4 are the cause of small patella syndrome (SPS) [MIM:147891]; also known as ischiopatellar dysplasia or Scott-Taor syndrome. SPS is an autosomal dominant skeletal dysplasia characterized by patellar aplasia or hypoplasia and by anomalies of the pelvis and feet, including disrupted ossification of the ischia and inferior pubic rami.
  • Sequence similarities
    Contains 1 T-box DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • SPS antibody
    • T box 4 antibody
    • T box protein 4 antibody
    • T box transcription factor TBX 4 antibody
    • T box transcription factor TBX4 antibody
    • T-box protein 4 antibody
    • T-box transcription factor TBX4 antibody
    • TBX 4 antibody
    • TBX4 antibody
    • TBX4_HUMAN antibody
    see all

Anti-Tbx4 antibody images

  • Anti-Tbx4 antibody (ab28634) at 0.5 µg/ml + HepG2 cell lysate 10ug.

    Secondary
    HRP conjugated anti-Rabbit IgG at 1: 50,000 - 100,000

    Predicted band size : 60 kDa
    Observed band size : 59 kDa (why is the actual band size different from the predicted?)

References for Anti-Tbx4 antibody (ab28634)

ab28634 has not yet been referenced specifically in any publications.

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Lamento mucho las molestias, y te reconozco que me ha sorprendido la perdida de actividad del anticuerpo si se ha mantenido en las condiciones recomend...

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