Recombinant Anti-Tetranectin antibody [EPR3067] (ab108999)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR3067] to Tetranectin
- Suitable for: WB, IHC-P
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-Tetranectin antibody [EPR3067]
See all Tetranectin primary antibodies -
Description
Rabbit monoclonal [EPR3067] to Tetranectin -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details
Unsuitable for: Flow Cyt -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Human fetal kidney and Human plasma lysates; Human kidney tissue.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.5% BSA -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR3067 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab108999 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (1) |
1/1000 - 1/10000. Detects a band of approximately 22 kDa (predicted molecular weight: 23 kDa).
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IHC-P |
1/500 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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WB
1/1000 - 1/10000. Detects a band of approximately 22 kDa (predicted molecular weight: 23 kDa). |
IHC-P
1/500 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis. -
Tissue specificity
Found in plasma. -
Sequence similarities
Contains 1 C-type lectin domain. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 7123 Human
- Entrez Gene: 21922 Mouse
- Entrez Gene: 316099 Rat
- Omim: 187520 Human
- SwissProt: P05452 Human
- SwissProt: P43025 Mouse
- Unigene: 476092 Human
- Unigene: 34588 Mouse
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Alternative names
- C type lectin domain family 3 member B antibody
- C-type lectin domain family 3 member B antibody
- Clec3b antibody
see all
Images
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All lanes : Anti-Tetranectin antibody [EPR3067] (ab108999) at 1/1000 dilution
Lane 1 : Human fetal kidney lysate
Lane 2 : Human plasma lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 23 kDa -
ab108999 at 1/500 dilution staining Tetranectin in Human kidney by Immunohistochemistry, Paraffin-embedded tissue.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab108999 has been referenced in 5 publications.
- Liu F et al. The adipocyte-enriched secretory protein tetranectin exacerbates type 2 diabetes by inhibiting insulin secretion from β cells. Sci Adv 8:eabq1799 (2022). PubMed: 36129988
- Sun J et al. CLEC3B as a potential diagnostic and prognostic biomarker in lung cancer and association with the immune microenvironment. Cancer Cell Int 20:106 (2020). PubMed: 32265595
- Storer MA et al. Acquisition of a Unique Mesenchymal Precursor-like Blastema State Underlies Successful Adult Mammalian Digit Tip Regeneration. Dev Cell 52:509-524.e9 (2020). PubMed: 31902657
- Zhu HF et al. Cancer-associated fibroblasts promote colorectal cancer progression by secreting CLEC3B. Cancer Biol Ther 20:967-978 (2019). PubMed: 30894065
- Liu J et al. CLEC3B is downregulated and inhibits proliferation in clear cell renal cell carcinoma. Oncol Rep 40:2023-2035 (2018). PubMed: 30066941