Overview

  • Product nameTetrodotoxin citrate
  • Description
    Na+ channel blocker; water-soluble
  • Alternative names
    • TTX
    • TTX citrate
  • Biological descriptionWater soluble citrate salt of tetrodotoxin. Potent, selective and reversible, use-dependent inhibitor of voltage-dependent Na+ channels.
  • Purity> 98%
  • General notes

    Country restrictions and/or license requirements may apply. Please contact customer services for further details.

Properties

    Tetrodotoxin citrate images

    • Cell-attached recording of a striatal cholinergic interneuron depicting TTX (100 nM) inhibition of spontaneous action potential firing. The open bar indicates time of TTX application.
    • Quantification of the p-S6rp signal in each striatal ChAt immunoreactive neuron after 1 hour incubation in control or TTX (1 M). Each dot corresponds to one neuron; each color corresponds to a different animal; dashed lines indicate the mean. Fluorescence values are normalized in arbitrary units (a.u.).

    References for Tetrodotoxin citrate (ab120055)

    This product has been referenced in:

    See all 28 Publications for this product

    Product Wall

    The water-soluble TTX citrate ab120055 is not a citrate salt, it is simply TTX that has been dissolved in a citrate solution, and then lyophilized. So, it has the same molecular weight and formula as ab120054, which is soluble in pH 4.8 citrate buffer ...

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    I contacted the laboratory regarding the difference between ab120054 and ab120055, and they responded that the only difference between these two compounds is that TTX citrate (ab120055) is the water soluble version, which accounts for the differen...

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    Tetrodotoxin is very toxic and should be handled with caution. The safety datasheet is available from the datasheet.

    Additionally, to neutralize the toxin, you may use a freshly made solution of 0.25% NaOCl + 0.25 N NaOH or a solution of 0.5%...

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    Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products.

    I am sorry this product did not perform as stated on the datasheet and for the inconvenience this...

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    Thank you for your technical enquiry.

    I am sorry that you are experiencing problems with your tetrodotoxin citrate. Before reaching our customers each batch is biologically tested for its ability to block sodium channels. No issues were repor...

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    Thank you for your email. I am sorry to hear that you are experiencing difficulties with these products.

    We are happy to investigate the products further however we would like to have more information. Could you answer the following questions...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"