AbcamBiochemicals

Thioflavin T (ab120751)

Overview

  • Product nameThioflavin T
  • Description
    Fluorescent cell permeable amyloid binding benzothiazole salt
  • Biological descriptionFluorescent cell permeable amyloid binding benzothiazole salt. Dye used to visualise stacked β sheets in vitro and in vivo. Binding induces a shift in excitation maximum (385 nm to 450 nm) and emission maximum (445 nm to 482 nm). Highly soluble in water. Limited ability to cross the blood-brain barrier.
  • Purity> 97%

Properties

    References for Thioflavin T (ab120751)

    This product has been referenced in:
    • Biancalana M & Koide S Molecular mechanism of Thioflavin-T binding to amyloid fibrils. Biochim Biophys Acta 1804:1405-12 (2010). Read more (PubMed: 20399286) »
    • Darghal N  et al. Mechanism of thioflavin T accumulation inside cells overexpressing P-glycoprotein or multidrug resistance-associated protein: role of lipophilicity and positive charge. Biochem Biophys Res Commun 343:623-9 (2006). Read more (PubMed: 16554036) »

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    Product Wall

    Thioflavin T has widely been used in frozen tissue so this product should work in frozen tissue.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"