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AbcamBiochemicals (Asc-021)

Thioperamide maleate (ab120021)

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Overview

  • Product nameThioperamide maleate
  • Description
    Potent, selective H3 antagonist
  • Biological descriptionPotent, selective H3 antagonist that crosses the blood-brain barrier.
  • Purity> 99%

    • Properties

  • Chemical nameN-Cyclohexyl-4-(imidazol-4-yl)-1-piperidinecarbothioamide maleate
  • Molecular Weight408.51
  • Chemical structureChemical Structure
  • Molecular formulaC15H24N4S.C4H4O4
  • CAS Number106243-16-7
  • PubChem identifier11211984
  • Storage instructionsStore at +4°C (desiccating conditions).
  • Solubility overviewSoluble in water to 50 mM
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • SMILESS=C(NC1CCCCC1)N2CCC(CC2)c3cncn3.O=C(O)/C=CC(=O)O
  • Source

    Synthetic

  • Research Areas

    • References for Thioperamide maleate (ab120021)

    This product has been referenced in:
    • van der Goot H & Timmerman H Selective ligands as tools to study histamine receptors. Eur J Med Chem 35:5-20 (2000). Read more (PubMed: 10733599) »
    • Alves-Rodrigues A  et al. [3H]-thioperamide as a radioligand for the histamine H3 receptor in rat cerebral cortex. Br J Pharmacol 118:2045-52 (1996). Read more (PubMed: 8864541) »
    • Mochizuki T  et al. Brain penetration of the histamine H3 receptor antagonists thioperamide and clobenpropit in rat and mouse, determined with ex vivo [125I]iodophenpropit binding. Brain Res 743:178-83 (1996). Read more (PubMed: 9017245) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"