Thymidine, Pyrimidine deoxynucleoside (ab143719)
Key features and details
- Pyrimidine deoxynucleoside. Potent thymidine kinase substrate.
- CAS Number: 50-89-5
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Thymidine, Pyrimidine deoxynucleoside -
Description
Pyrimidine deoxynucleoside. Potent thymidine kinase substrate. -
Biological description
Pyrimidine deoxynucleoside. Potent thymidine kinase substrate (IC50 = 16 nM). Pairs with deoxyadenosine in double-stranded DNA. Synchronizes cells in S phase in vivo. -
Purity
> 98% -
CAS Number
50-89-5 -
Chemical structure
Properties
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Chemical name
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione -
Molecular weight
242.23 -
Molecular formula
C10H14N2O5 -
PubChem identifier
5789 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab143719 has been referenced in 2 publications.
- Li B et al. Mechanical phenotyping reveals unique biomechanical responses in retinoic acid-resistant acute promyelocytic leukemia. iScience 25:103772 (2022). PubMed: 35141508
- Lastra D et al. Transcription Factor NRF2 Participates in Cell Cycle Progression at the Level of G1/S and Mitotic Checkpoints. Antioxidants (Basel) 11:N/A (2022). PubMed: 35624810