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Product Name
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Thyroglobulin antibody
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See all Thyroglobulin antibodies (19)...
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Product type
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Primary antibodies
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Description
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Sheep polyclonal to Thyroglobulin
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Immunogen
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Full length native protein: Affinity purified human Thyroglobulin.
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Reacts with
(species key)
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Hu
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Specificity
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This antibody recognizes Thyroglobulin: 100%.
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Tested applications
(see key)
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RIA
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Abreviews
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Application notes
(see key)
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Recommended dilutions
RIA: 1/45000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Cancer >> Tumor biomarkers >> Globulins
Signal Transduction >> Growth Factors/Hormones >> Hormones
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Relevance
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Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Sheep
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: 0.1% Sodium Azide.
Constituents: 40% Glycerol, Whole serum. Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Thyroglobulin antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Thyroglobulin
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Thyroglobulin antibody - more information
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Customer reviews (feedback) regarding Thyroglobulin antibody |
Customer FAQs regarding Thyroglobulin antibody |
Protocols for Thyroglobulin antibody |
Price and availability of products related to Thyroglobulin antibody |
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Thyroglobulin antibody - related products:
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Thyroglobulin antibody - other tools:
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Contact Abcam with a Technical Enquiry about Thyroglobulin antibody |
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