You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Anti-Thyroid Hormone Receptor alpha 1+2 antibody, prediluted (ab15544)

Submit an Abreview Q&A (1)

Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab15544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IHC-P
  • Application notesIHC-P: Use at an assay dependent dilution. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionNuclear hormone receptor. High affinity receptor for triiodothyronine.
    • Involvement in diseaseDefects in THRA are the cause of congenital hypothyroidism non-goitrous type 6 (CHNG6) [MIM:614450]. A disease characterized by growth retardation, developmental retardation, skeletal dysplasia, borderline low thyroxine levels and high triiodothyronine levels. There is differential sensitivity to thyroid hormone action, with retention of hormone responsiveness in the hypothalamic pituitary axis and liver but skeletal, gastrointestinal, and myocardial resistance.
    • Sequence similaritiesBelongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • DomainComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
    • Cellular localizationNucleus.

      • Target information above from: UniProt accession P10827 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      see all
    • Alternative names
        AR7 antibodyAvian erythroblastic leukemia viral (v erb a) oncogene homolog antibodyc ERBA 1 antibody
        c ERBA ALPHA 2 antibodyC erbA alpha antibodyc-erbA-1 antibodyC-erbA-alpha antibodycerbA protein antibodycerbAalpha antibodyEAR 7 antibodyEAR 7.1 antibodyEAR 7.2 antibodyEAR-7 antibodyEAR7 antibodyERB T 1 antibodyERBA 1 antibodyERBA ALPHA antibodyERBA antibodyERBA related 7 antibodyERBA1 antibodyErythroblastic leukemia viral (v erb a) oncogene homolog avian antibodyMGC000261 antibodyMGC43240 antibodyNR1A 1 antibodyNr1a1 antibodyNuclear receptor subfamily 1 group A member 1 antibodyOncogene ERBA antibodyTHA_HUMAN antibodyTHRA antibodyThra1 antibodyThra2 antibodyThyroid hormone receptor alpha 1 (avian erythroblastic leukemia viral (verba) oncogene homolog 1 formerly ERBA1) antibodyThyroid hormone receptor alpha 1 antibodyThyroid hormone receptor alpha 2 antibodyThyroid hormone receptor alpha antibodyTR alpha 1 antibodyTR alpha 2 antibodyTra1 antibodyTriiodothyronine receptor antibodyV-erbA-related protein 7 antibody
      see all

    Anti-Thyroid Hormone Receptor alpha 1+2 antibody, prediluted images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thyroid Hormone Receptor alpha 1+2 antibody, prediluted (ab15544)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thyroid Hormone Receptor alpha 1+2 antibody, prediluted (ab15544)

      ab15544 staining thyroid hormone receptor alpha 1 and 2 in colon carcinoma by Immunohistochemistry (formalin/paraffin).

    References for Anti-Thyroid Hormone Receptor alpha 1+2 antibody, prediluted (ab15544)

    ab15544 has not yet been referenced specifically in any publications.

    Publishing research using ab15544 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab15544 Submit a Question for ab15544

    Displaying 1 - 1 of 1 results for Abreviews and Q&A

    10
    Votes: Highest First

    I just left a voice message with technical service. Below is the specific question that I have. There are several TR alpha and TR beta specific antibodies that you sell. I was wondering if you also sell the peptides for them. The catalog numbers of th...

    Read More

    Thank you for your enquiry. Unfortunately, we don't have the corresponding peptides for these antibodies. If you cannot find what you are looking for within the Abcam catalogue, you can click on the link to "The World's Antibody Gateway". The World's A...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"