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Anti-Thyroid Hormone Receptor alpha 2 antibody (ab97887)

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Overview

  • Product nameAnti-Thyroid Hormone Receptor alpha 2 antibodySee all Thyroid Hormone Receptor alpha 2 primary antibodies ...
  • Description
    Rabbit polyclonal to Thyroid Hormone Receptor alpha 2
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to amino acids 317-490 of Human Thyroid Hormone Receptor alpha 2 (Uniprot ID: P10827)

  • Positive controlJurkat cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 1% BSA, PBS, pH 7
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab97887 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/500 - 1/3000. Predicted molecular weight: 55 kDa.

Target

  • RelevanceThyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory. Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors, TRalpha1, TRalpha2, TRbeta1 and TRbeta2. TRalpha1, TRbeta1 and TRbeta2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain.
  • Cellular localizationNuclear
  • Database links
    • Alternative names
        EAR7 antibodyERBA1 antibodyTHRA antibody
        Thyroid hormone receptor alpha 2 antibodyThyroid hormone receptor alpha antibodyTR alpha 2 antibody
      see all

    Anti-Thyroid Hormone Receptor alpha 2 antibody images

    • Western blot - Anti-Thyroid Hormone Receptor alpha 2 antibody (ab97887)
      Western blot - Anti-Thyroid Hormone Receptor alpha 2 antibody (ab97887)
      Anti-Thyroid Hormone Receptor alpha 2 antibody (ab97887) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

      Predicted band size : 55 kDa

    References for Anti-Thyroid Hormone Receptor alpha 2 antibody (ab97887)

    ab97887 has not yet been referenced specifically in any publications.

    Publishing research using ab97887 ? Please let us know so that we can cite the reference in this datasheet

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    Is this antibody specific for Thyroid Hormone Receptor alpha 1 or 2?

    Thank you for contacting Abcam regarding our Thyroid Hormone Receptor Alpha antibodies.


    Regarding ab53729, I have confirmed that this antibody will react with alpha-1, -2, -3, and -4 and is NOT specific for alpha 1. The immunogen range is co...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"