You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Anti-Thyroid Hormone Receptor alpha 2 antibody [1330] (ab30582)

Submit an Abreview Submit a Question

Overview

  • Product nameAnti-Thyroid Hormone Receptor alpha 2 antibody [1330]See all Thyroid Hormone Receptor alpha 2 primary antibodies ...
  • Description
    Mouse monoclonal [1330] to Thyroid Hormone Receptor alpha 2
  • Specificityab30582 recognises Thyroid Hormone Receptor alpha 2.
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to amino acid residues from the N terminal region of human thyroid hormone receptor, alpha2 isotype.

  • Positive controlHuman hippocampal lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 50% Glycerol, 0.1mg/ml BSA, 150mM Sodium chloride, 10mM HEPES. pH 7.5
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesab30582 was purified from mouse ascites by ammonium sulfate precipitation prior to affinity purification on a Protein G column.
  • Clonality Monoclonal
  • Clone number1330
  • IsotypeIgG1
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab30582 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/1000. Detects a band of approximately 55 kDa (predicted molecular weight: 55 kDa).

Target

  • RelevanceThyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory. Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors, TRalpha1, TRalpha2, TRbeta1 and TRbeta2. TRalpha1, TRbeta1 and TRbeta2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain.
  • Cellular localizationNuclear
  • Database links
    • Alternative names
        c erbA 1 antibodyC erbA alpha antibodyEAR7 antibody
        ERBA1 antibodyNR1A1 antibodyTHRA antibodyThyroid hormone receptor alpha 2 antibodyThyroid hormone receptor alpha antibodyTR alpha 2 antibody
      see all

    Anti-Thyroid Hormone Receptor alpha 2 antibody [1330] images

    • Western blot - Thyroid Hormone Receptor alpha 2 antibody [1330] (ab30582)
      Western blot - Thyroid Hormone Receptor alpha 2 antibody [1330] (ab30582)
      Anti-Thyroid Hormone Receptor alpha 2 antibody [1330] (ab30582) at 1/1000 dilution + human hippocampal lysate

      Predicted band size : 55 kDa
      Observed band size : 55 kDa
      Additional bands at : 90 kDa. We are unsure as to the identity of these extra bands.

    References for Anti-Thyroid Hormone Receptor alpha 2 antibody [1330] (ab30582)

    ab30582 has not yet been referenced specifically in any publications.

    Publishing research using ab30582 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab30582 Submit a Question for ab30582

    There are currently no Abreviews or Questions for ab30582.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"