Overview
- Product nameAnti-Thyroid Hormone Receptor antibodySee all Thyroid Hormone Receptor primary antibodies ...
- DescriptionRabbit polyclonal to Thyroid Hormone Receptor
- Tested applicationsWB more details
- Species reactivityReacts with: Human
- Immunogen
Full length protein, corresponding to amino acids 1-410 of Human Thyroid Hormone Receptor (NP_955366.1)
- Positive controlHepG2 cell lysate and Thyroid Hormone Receptor transfected 293T cell lysate
Properties
- FormLiquid
- Storage instructionsStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Storage bufferPreservative: None
Constituents: 1X PBS, pH 7.2 -
Concentration information loading... - PurityProtein A purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab103815 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: 1/500. Predicted molecular weight: 54 kDa. |
Target
- RelevanceThyroid hormone receptors (TRs) are ligand dependent members of the steroid/retinoic acid superfamily of transcription factors. The two genes encoding TRs identified to date, TR alpha and TR beta, have been mapped to human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half site binding motifs in the orientation of palindromes, direct repeats, or inverted palindromes. The affinities of binding are both variable and influenced differentially by 3,5,3 triiodo L thyronine (T3). Thyroid hormones, through their interaction with the TR affect metabolic processes, growth and development.
- Cellular localizationNuclear
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Database links
- Entrez Gene: 7067 Human
- Entrez Gene: 7068 Human
- Omim: 190120 Human
- Omim: 190160 Human
- SwissProt: P10827 Human
- SwissProt: P10828 Human
- Unigene: 724 Human
- Unigene: 187861 Human
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Alternative names
- ERBA ALPHA antibodyERBA beta antibodyERBA1 antibody
- ERBA2 antibodyNR1A1 antibodyNR1A2 antibodyTHR1 antibodyTHRA antibodyTHRA1 antibodyTHRA2 antibodyTHRB antibodyTHRB1 antibodyTHRB2 antibodyThyroid hormone receptor alpha antibodyThyroid hormone receptor beta antibody
see all
Anti-Thyroid Hormone Receptor antibody images
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Western blot - Thyroid Hormone Receptor antibody (ab103815)Anti-Thyroid Hormone Receptor antibody (ab103815) at 1/500 dilution + HepG2 cell lysate at 50 µg
Predicted band size : 54 kDa -
Western blot - Thyroid Hormone Receptor antibody (ab103815)All lanes : Anti-Thyroid Hormone Receptor antibody (ab103815) at 1/500 dilution
Lane 1 : Thyroid Hormone Receptor transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Predicted band size : 54 kDa
References for Anti-Thyroid Hormone Receptor antibody (ab103815)
ab103815 has not yet been referenced specifically in any publications.
