Tobramycin, free base, Ribosomal translation inhibitor (ab120659)
Key features and details
- Ribosomal translation inhibitor
- CAS Number: 32986-56-4
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Tobramycin, free base, Ribosomal translation inhibitor -
Description
Ribosomal translation inhibitor -
Biological description
Inhibits ribosomal translation. Aminoglycoside antibiotic which binds 30S ribosomal subunit A, preventing functional protein production. Effective against gram-negative bacteria.
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Purity
> 98% -
CAS Number
32986-56-4 -
Chemical structure
Properties
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Chemical name
O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1→4)]-2-deoxy-D-streptamine -
Molecular weight
467.50 -
Molecular formula
C18H37N5O9 -
PubChem identifier
36294 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab120659 has been referenced in 1 publication.
- Beznosková P et al. Yeast applied readthrough inducing system (YARIS): an invivo assay for the comprehensive study of translational readthrough. Nucleic Acids Res 47:6339-6350 (2019). PubMed: 31069379