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Products:Neuroscience >> Neurology process >> Neurodegenerative disease >> Parkinson's disease >> Other
Overview
Product name
Torsin A peptide
See all Torsin A products (3) ...
Protein description
Synthetic peptide derived from within residues 300 to the C-terminus of Rat Torsin A.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab34540 - Torsin A antibody.
Protein length
333 amino acids
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
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Research areas
Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Neurology process >> Growth and Development >> Axonal Guidance Proteins
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
Neuroscience >> Neurology process >> Neurodegenerative disease >> Parkinson's disease >> Other
Applications
Application notes
This peptide can be used with studies using ab34540.
Protein info
Relevance
Mutations in Torsin A (Dyt1 gene) causes early onset torsin dystonia, a movement disorder involving dysfunction in the basal ganglia without apparent neurodegeneration. Most cases result from a dominantly acting three-base pair deletion in the Dyt1 gene causing loss of a glutamic acid near the carboxyl terminus of Torsin A. Torsins are members of the AAA(+) superfamily of ATPases and are present in all multicellular organisms. Torsin A is an ER protein involved in chaperone functions and/or membrane movement. Torsins are also implicated in neurogenesis, neuronal migration, axon/dendrite development and synaptogenesis.
Cellular localization
Endoplasmic reticulum
References for Torsin A peptide (ab35510)
ab35510 has not yet been referenced specifically in any publications.
Publishing research using ab35510? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"