Overview
Product nameToxoplasma gondii p30 proteinSee all Toxoplasma gondii p30 proteins and peptides ...
Protein descriptionRecombinant fragment, corresponding to amino acids 45-198 of Toxoplasma gondii p30, containing the p30 immunodominant regions.
Expression hostE. coli
Properties
Purity> 95
% by SDS-PAGE
Purification notesab68110 was purified by a proprietary chromatographic technique.
Biological activityab68110 is immunoreactive with sera of Toxoplasma gondii-infected individuals.
FormLiquid
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: None
Constituents: 50% Glycerol, 1.5M Urea, 50mM Tris HCl
Concentration information loading...
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab68110
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|
Application
|
Notes |
| WB |
WB: Use at an assay dependent dilution. Predicted molecular weight: 56 kDa. |
| ELISA |
ELISA: Use at an assay dependent dilution. |
Protein info
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Alternative names
Major surface antigen p30p30SAG1SAG1 protein
RelevanceToxoplasma gondii p30 is the immunodominant surface antigen of Toxoplasma gondii.
Toxoplasma gondii is an obligate intracellular protozoan that belongs to the class Sporozoa, and the order Eucoccidia. The parasite has an extremely wide host range and is also nonspecific with respect to the kind of cell type it can enter, making it an interesting model to study invasion. Although toxoplasmosis in healthy adults is generally asymptomatic, it produces severe disease in neonates and immunocompromised people, being the cause of death in many AIDS patients.
P30 is the major surface antigen of T. gondii. It is a very abundant protein, conserved in most strains, and present both in the vesicular network of the parasitophorous vacuole and on the surface of the parasite. It is very immunogenic, eliciting high titers of antibodies in infected individuals. The gene coding for P30 has been cloned and completely sequenced: the deduced amino acid sequence shows a putative signal sequence at the N terminus, consistent with localization of P30 on the parasite’s surface, as well as a short hydrophobic stretch at the C terminus.
References for Toxoplasma gondii p30 protein (ab68110)
ab68110
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
