Overview

  • Product nameAnti-Transglutaminase antibody
    See all Transglutaminase primary antibodies
  • Description
    Rabbit polyclonal to Transglutaminase
  • SpecificityThis antibody is specific to keratinocyte Transglutaminase 1.
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A 15 residue synthetic peptide derived from a domain specific for Transglutaminase 1 protein.

Applications

Our Abpromise guarantee covers the use of ab27000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/1000. Predicted molecular weight: 90 kDa.

Target

  • RelevanceTissue transglutaminase is a calcium activated enzyme which catalyzes the cross linking of proteins and the conjugation of polyamines to proteins. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD). CD, a genetic, immunologically mediated small bowel enteropathy that causes malabsorption, is a relatively common disorder in Western countries.
  • Alternative names
    • Epidermal TGase antibody
    • ICR 2 antibody
    • ICR2 antibody
    • K polypeptide epidermal type I antibody
    • KTG antibody
    • LI 1 antibody
    • LI antibody
    • LI1 antibody
    • Protein glutamine gamma glutamyltransferase K antibody
    • TG(K) antibody
    • TGase 1 antibody
    • TGASE antibody
    • TGase K antibody
    • TGase1 antibody
    • TGaseK antibody
    • TGK antibody
    • Tgm 1 antibody
    • Tgm1 antibody
    • Transglutaminase 1 antibody
    • Transglutaminase K antibody
    • Transglutaminase keratinocyte antibody
    • Transglutaminase1 antibody
    • TransglutaminaseK antibody
    see all

Anti-Transglutaminase antibody images

  • Anti-Transglutaminase antibody (ab27000) at 1/200 dilution + an extract from human epidermis.

    Predicted band size : 90 kDa
    Observed band size : 90 kDa
  • Anti-Transglutaminase antibody (ab27000) at 1/500 dilution + Human recombinant Transglutaminase at 0.5 µg

    Secondary
    HRP-conjugated anti Rabbit IgG at 1/5000 dilution

    Predicted band size : 90 kDa
    Observed band size : 90 kDa

References for Anti-Transglutaminase antibody (ab27000)

This product has been referenced in:
  • Mallery SR  et al. Topical application of a mucoadhesive freeze-dried black raspberry gel induces clinical and histologic regression and reduces loss of heterozygosity events in premalignant oral intraepithelial lesions: results from a multicentered, placebo-controlled clinical trial. Clin Cancer Res 20:1910-24 (2014). WB ; Human . Read more (PubMed: 24486592) »
  • Grall A  et al. PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans. Nat Genet 44:140-7 (2012). Read more (PubMed: 22246504) »

See all 2 Publications for this product

Product Wall

Merci de votre intérêt pour le ab27000.

Anotre connaissance cet anticorps n’a pas encore été testé en IHC-Fr et nous n’offrons pas d’échantillon gratuit à des fins de tests pr&...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"