Anti-Transglutaminase antibody (ab27000)
Overview
- Product nameAnti-Transglutaminase antibodySee all Transglutaminase primary antibodies ...
- DescriptionRabbit polyclonal to Transglutaminase
- SpecificityThis antibody is specific to keratinocyte Transglutaminase 1.
- Tested applicationsWB more details
- Species reactivityReacts with: Human
- Immunogen
A 15 residue synthetic peptide derived from a domain specific for Transglutaminase 1 protein.
Properties
- FormLiquid
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: Whole serum - PurityWhole antiserum
- Clonality Polyclonal
- IsotypeIgG
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Research Areas
Applications
Our Abpromise guarantee covers the use of ab27000 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: 1/200 - 1/1000. Predicted molecular weight: 90 kDa. |
Target
- RelevanceTissue transglutaminase is a calcium activated enzyme which catalyzes the cross linking of proteins and the conjugation of polyamines to proteins. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD). CD, a genetic, immunologically mediated small bowel enteropathy that causes malabsorption, is a relatively common disorder in Western countries.
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Alternative names
- Epidermal TGase antibodyICR 2 antibodyICR2 antibody
- K polypeptide epidermal type I antibodyKTG antibodyLI 1 antibodyLI antibodyLI1 antibodyProtein glutamine gamma glutamyltransferase K antibodyTG(K) antibodyTGase 1 antibodyTGASE antibodyTGase K antibodyTGase1 antibodyTGaseK antibodyTGK antibodyTgm 1 antibodyTgm1 antibodyTransglutaminase 1 antibodyTransglutaminase K antibodyTransglutaminase keratinocyte antibodyTransglutaminase1 antibodyTransglutaminaseK antibody
see all
Anti-Transglutaminase antibody images
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Western blot - Transglutaminase antibody (ab27000)Anti-Transglutaminase antibody (ab27000) at 1/200 dilution + an extract from human epidermis.
Predicted band size : 90 kDa
Observed band size : 90 kDa -
Western blot - Transglutaminase antibody (ab27000)Anti-Transglutaminase antibody (ab27000) at 1/500 dilution + Human recombinant Transglutaminase at 0.5 µg
Secondary
HRP-conjugated anti Rabbit IgG at 1/5000 dilution
Predicted band size : 90 kDa
Observed band size : 90 kDa
References for Anti-Transglutaminase antibody (ab27000)
This product has been referenced in:
- Grall A et al. PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans. Nat Genet 44:140-7 (2012). Read more (PubMed: 22246504) »
