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Products:Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Splicing
Overview
Product name
U1A peptide
Protein description
Synthetic peptide derived from within residues 150 - 250 of Human U1A.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab40689 - U1A antibody.
Protein length
282 amino acids
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
Concentration information loading...
Research areas
Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Splicing
Applications
Application notes
This peptide can be used with studies using ab40689.
Protein info
Function
Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.
Sequence similarities
Belongs to the RRM U1 A/B'' family.
Contains 2 RRM (RNA recognition motif) domains.
Cellular localization
Nucleus.
Target information above from: UniProt accessionP09012
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for U1A peptide (ab41553)
ab41553 has not yet been referenced specifically in any publications.
Publishing research using ab41553? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"