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Overview

  • Product nameAnti-UAP1 antibodySee all UAP1 primary antibodies ...
  • Description
    Rabbit polyclonal to UAP1
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide: LKDANDVPIQ CEISPLISYA GEGLEGYVAD KEFHAPLIID ENGVHELVKN , corresponding to a region within the C terminal amino acids 471-520 of Human UAP1 (NP_598567).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive controlMouse brain lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab113887 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use a concentration of 1 µg/ml. Predicted molecular weight: 59 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionConverts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
  • Tissue specificityWidely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.
  • PathwayNucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.
  • Sequence similaritiesBelongs to the UDPGP type 1 family.
  • Cellular localizationCytoplasm. In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.

    • Target information above from: UniProt accession Q16222 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    see all
  • Alternative names
      AGX 1 antibodyAGX antibodyAGX-1 antibody
      AGX-2 antibodyAGX1 antibodyAntigen X antibodyAntigenX antibodySPAG 2 antibodySPAG2 antibodySperm associated antigen 2 antibodySperm-associated antigen 2 antibodyUAP 1 antibodyuap1 antibodyUAP1_HUMAN antibodyUDP N acetylhexosamine pyrophosphorylase antibodyUDP N acteylglucosamine pyrophosphorylase 1 antibodyUDP-N-acetylglucosamine pyrophosphorylase antibody
    see all

Anti-UAP1 antibody images

  • Western blot - UAP1 antibody (ab113887)
    Western blot - UAP1 antibody (ab113887)
    Anti-UAP1 antibody (ab113887) at 1 µg/ml + Mouse brain lysate at 10 µg

    Predicted band size : 59 kDa

References for Anti-UAP1 antibody (ab113887)

ab113887 has not yet been referenced specifically in any publications.

Publishing research using ab113887 ? Please let us know so that we can cite the reference in this datasheet

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