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Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab58211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionConverts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
    • Tissue specificityWidely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.
    • PathwayNucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.
    • Sequence similaritiesBelongs to the UDPGP type 1 family.
    • Cellular localizationCytoplasm. In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.

      • Target information above from: UniProt accession Q16222 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          AGX 1 antibodyAGX antibodyAGX-1 antibody
          AGX-2 antibodyAGX1 antibodyAntigen X antibodyAntigenX antibodySPAG 2 antibodySPAG2 antibodySperm associated antigen 2 antibodySperm-associated antigen 2 antibodyUAP 1 antibodyuap1 antibodyUAP1_HUMAN antibodyUDP N acetylhexosamine pyrophosphorylase antibodyUDP N acteylglucosamine pyrophosphorylase 1 antibodyUDP-N-acetylglucosamine pyrophosphorylase antibody
        see all

      Anti-UAP1 antibody images

      • Western blot - UAP1 antibody (ab58211)
        Western blot - UAP1 antibody (ab58211)
        Western blot against tagged recombinant protein immunogen using ab58211 UAP1 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

      References for Anti-UAP1 antibody (ab58211)

      ab58211 has not yet been referenced specifically in any publications.

      Publishing research using ab58211 ? Please let us know so that we can cite the reference in this datasheet

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