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Anti-UBASH3A antibody (ab59122)

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Overview

Product name

Anti-UBASH3A antibody
See all UBASH3A products (3) ...

Description

Goat polyclonal to UBASH3A

Specificity

ab59122 is expected to recognize both reported isoforms (NP_061834.1 and NP_001001895.1).

Tested applications

ELISA, IHC-Pmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Dog

Immunogen

Synthetic peptide: QQCSTPDGKYYRPD, corresponding to internal sequence amino acids 417-430 of Human UBASH3A

QQCSTPDGKY YRPD

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

Daudi cell lysate.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Purification notes

ab59122 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Clonality

Polyclonal

Isotype

IgG

Research areas

Cell Biology >> Other Antibodies >> Other Antibodies

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - UBASH3A antibody (ab59122)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - UBASH3A antibody (ab59122) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab59122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ELISA

     ELISA: 1/64000

    ELISA: 1/64000

  • ShowHide1 Image

    IHC-P

     IHC-P: Use a concentrati...Read more →

    IHC-P: Use a concentration of 2.5 µg/mlPerform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

Relevance

UBASH3A, ubiquitin associated and SH3 domain containing, A, interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface (referenced from Swiss Prot).

Cellular localization

Cytoplasmic and Nuclear

Alternative names

  • Cbl interacting protein 4 antibody
  • CLIP4 antibody
  • STS 2 antibody
  • Suppressor of T cell receptor signaling 2 antibody
  • T cell ubiquitin ligand antibody
  • TULA antibody
  • UBASH3A antibody
  • ubiquitin associated and SH3 domain containing, A antibody
see all

Database links

Anti-UBASH3A antibody images:

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - UBASH3A antibody (ab59122)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - UBASH3A antibody (ab59122)

ab59122 (2.5 µg/ml) staining UBASH3A in human spleen by IHC-P.  Steamed antigen retrieval with citrate buffer pH 6, AP-staining.  The image shows cytoplasm staining of T-cells eccentrically gathered around an artery.

References for Anti-UBASH3A antibody (ab59122)

ab59122 has not yet been referenced specifically in any publications.

Publishing research using ab59122? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"