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Western blot - UBE2Q2 antibody (ab57950)
(enlarge)
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Product Name
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UBE2Q2 antibody
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See all UBE2Q2 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to UBE2Q2
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Immunogen
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Recombinant fragment, corresponding to amino acids 1-111 of Human UBE2Q2
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Reacts with
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Hu
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Tested applications
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WB
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Abreviews
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Application notes
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasm
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Research areas
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Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Ubiquitylation
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Relevance
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The ubiquitination pathway is known to regulate critical control points in multiple cellular processes by targeting proteins for activation, degradation, or localization at specific intracellular sites. The pathway
involves an enzymatic cascade in which the first step activates ubiquitin by forming a high energy thiolester intermediate to ubiquitin activating enzyme (E1) that is subsequently transferred to members of an E2 ubiquitin conjugating enzyme superfamily. The E2 ubiquitin conjugating
45 enzymes function together with a larger superfamily of E3 ubiquitin ligases to transfer activated ubiquitin to specific cellular proteins. The existence of E2 and E3 superfamilies reflects the specificity of each E2-E3 cognate pair for a specific group of cellular substrates. UBE2Q2 is a potentially unique member of the ubiquitin conjugating enzyme superfamily that includes at least 17 phenotypically different subfamilies, many of which contain isozymes.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2a
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this UBE2Q2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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UBE2Q2 antibody images:
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 Western blot - UBE2Q2 antibody (ab57950)
Predicted band size : 43 kDa
UBE2Q2 antibody (ab57950) at 1ug/lane + A-431 cell lysate at 25ug/lane.
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Search PubMed (MEDLINE) for references to UBE2Q2
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UBE2Q2 antibody - more information
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Customer reviews (feedback) regarding UBE2Q2 antibody |
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UBE2Q2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about UBE2Q2 antibody |
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