Anti-UPP2 antibody (ab153861)
Key features and details
- Rabbit polyclonal to UPP2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-UPP2 antibody -
Description
Rabbit polyclonal to UPP2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 1-217 of Human UPP2.
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Positive control
- 293T, A431, HeLa and HepG2 cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab153861 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 36 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 36 kDa. |
Target
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Function
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. -
Tissue specificity
Predominantly expressed in kidney. -
Pathway
Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1. -
Sequence similarities
Belongs to the PNP/UDP phosphorylase family. - Information by UniProt
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Database links
- Entrez Gene: 534937 Cow
- Entrez Gene: 151531 Human
- Entrez Gene: 76654 Mouse
- Entrez Gene: 295620 Rat
- SwissProt: O95045 Human
- SwissProt: Q8CGR7 Mouse
- Unigene: 128427 Human
- Unigene: 200370 Mouse
see all -
Alternative names
- Liver specific uridine phosphorylase antibody
- UDRPASE2 antibody
- UP2 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab153861 has not yet been referenced specifically in any publications.