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Products:Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper
Overview
Product name
Anti-USF1 antibody
See all USF1 products (6) ...
Description
Rabbit polyclonal to USF1
Specificity
ab12128 recognises human USF1.
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide, corresponding to amino acids 1-14 of Human USF1.
Positive control
Jurkat nuclear extract.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.1% Sodium Azide, 0.01% Thimerosal (merthiolate)
Constituents: 0.2% Gelatin, PBS
Concentration
Concentration information loading...
Purity
Protein A purified
Purification notes
Affinity purified.
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Cancer Metabolism >> Response to hypoxia
Cardiovascular >> Atherosclerosis >> Diabetes associated
Cardiovascular >> Atherosclerosis >> Lipoprotein metabolism
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH / Leucine Zipper
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper
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Western blot - Anti-USF1 antibody (ab12128)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab12128 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
WB: 1/250 - 1/500. Detects a band of approximately 43 kDa (predicted molecular weight: 37.2 kDa). For optimal results, primary antibody incubations should be performed at 4°C.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
USF1 is a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E box motifs. USF1 has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this.
Cellular localization
Nuclear
Alternative names
- bHLHb11 antibody
- Class B basic helix-loop-helix protein 11 antibody
- FCHL 1 antibody
see all
Database links
- Entrez Gene: 7391 Human
- Omim: 191523 Human
- SwissProt: P22415 Human
- Unigene: 414880 Human
Anti-USF1 antibody images:
Western blot - Anti-USF1 antibody (ab12128)
Predicted band size : 37.2 kDa
Detection of USF1 by Western blot analysis. The presence of USF1 in nuclear extracts derived from the Jurkat cell line is confirmed using ab12128 at a 1:250 dilution (lane 1). As demonstrated in lane 2, the signal corresponding to USF1 is eliminated by incubating the reaction mixture together with the immunizing peptide.
References for Anti-USF1 antibody (ab12128)
ab12128 has not yet been referenced specifically in any publications.
Publishing research using ab12128? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"