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Products:Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper
Overview
Product name
Anti-USF1 antibody
See all USF1 products (6) ...
Description
Mouse monoclonal to USF1
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment, corresponding to amino acids 1-111 of Human USF1
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
kappa
Research areas
Cancer >> Cancer Metabolism >> Response to hypoxia
Cardiovascular >> Atherosclerosis >> Diabetes associated
Cardiovascular >> Atherosclerosis >> Lipoprotein metabolism
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH / Leucine Zipper
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper
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Western blot - USF1 antibody (ab58100)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab58100 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
USF1 is a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E box motifs. USF1 has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this.
Cellular localization
Nuclear
Alternative names
- bHLHb11 antibody
- Class B basic helix-loop-helix protein 11 antibody
- FCHL 1 antibody
see all
Database links
- Entrez Gene: 7391 Human
- Omim: 191523 Human
- SwissProt: P22415 Human
- Unigene: 414880 Human
Anti-USF1 antibody images:
Western blot - USF1 antibody (ab58100)
USF1 antibody (ab58100) at 1ug/lane + MCF-7 cell lysate at 25ug/lane.
References for Anti-USF1 antibody (ab58100)
This product has been referenced in:
- Wu Set al. Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice. Hum Mol Genet 19:597-608 (2010). WB.Read more (PubMed: 19995791) »
See 1 publication for this product
Publishing research using ab58100? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"